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Skin

Skin Hydration and Structural Integrity

60 gélules pour 1 mois

SKIN is the advanced Cellular Nutrition protocol formulated by the Dr. Espinasse to act deeply on the dermal matrix by supporting skin hydration, firmness, and antioxidant protection.


This food supplement combines hyaluronic acid, hydrolysed marine collagen, astaxanthin, and selected probiotic strains, chosen for their complementary and synergistic actions: together, they support deep hydration, dermal density, and the skin’s resistance to oxidative stress and ageing processes.


By targeting skin dehydration, loss of elasticity, collagen degradation, oxidative stress, and low-grade inflammation, SKIN helps improve firmness, texture, and radiance: its integrative formulation is particularly suited to skin affected by ageing, UV exposure, stress, pollution, or inflammaging.


SKIN is recommended in cases of dry skin and loss of elasticity, wrinkles and skin laxity, dull complexion or photo-ageing, as well as reactive, inflammation-prone, or inflammaging-affected skin: it forms part of a global skin health approach, supporting long-term hydration, structural integrity, and biological protection of the skin.

Key bioavailable active ingredients HYALURONIC ACID / MARINE COLLAGEN / ASTAXANTHIN

single bottle 75.00€
3-bottle pack -10% on pack of 3 : 67.50€ per unit instead of 75.00€
202.50€ 225€
select a quantity
vegetable capsule
vegan
gluten-free
lactose-free
GMO-free

Integrated actions & benefits

Through its comprehensive synergy, SKIN works at the heart of the skin’s structural and metabolic foundations, simultaneously targeting hydration, the dermal matrix and cellular protection. Its formulation supports extracellular matrix cohesion, improves the dermis’ water-retention capacity and promotes a biological environment conducive to skin regeneration. SKIN helps restore deep, long-lasting hydration while stimulating endogenous collagen production, which is essential for firmness, elasticity and the skin’s mechanical strength. At the same time, its antioxidant action helps limit the impact of oxidative stress, UV exposure and low-grade inflammation — key drivers of premature skin ageing and loss of radiance. By integrating the gut–skin axis, SKIN also helps soothe inflammatory tendencies, strengthen the skin barrier and improve overall skin quality, including in sensitive or reactive skin types. It is a key supplement for preserving skin youthfulness, supporting natural repair mechanisms and sustainably restoring radiance, density and firmness.

Integrated mechanisms of action

Deep hydration: water fixation and retention in the extracellular matrix (hyaluronic acid).

Structural reinforcement: stimulation of collagen and elastin synthesis (marine collagen).

Antioxidant protection: neutralisation of free radicals and mitochondrial protection (astaxanthin).

Regulation of skin inflammation: reduction of inflammaging and strengthening of the gut–skin barrier (probiotics).

Scientifically documented active ingredient synergy

  • Naturally present in the dermis, hyaluronic acid can bind up to 1,000 times its weight in water.
  • Its concentration decreases with age, leading to dryness, wrinkles, and loss of elasticity.
  • Oral supplementation, particularly in low molecular weight form, promotes deep hydration, improves skin plumpness, and stimulates endogenous hyaluronic acid production by fibroblasts.
  • It also helps soothe sensitive or inflammation-prone skin (rosacea, eczema, post-inflammatory acne).
  • Collagen accounts for nearly 80% of dermal proteins. Over time, degradation exceeds synthesis, leading to skin laxity.
  • Hydrolysed marine collagen peptides (molecular weight < 2000 Da) are efficiently absorbed and stimulate endogenous production of collagen types I and III.
  • They improve dermal density, firmness, and mechanical strength while reducing wrinkle depth.
  • Clinical studies have shown measurable improvements in hydration and elasticity after eight weeks of supplementation.
  • A carotenoid pigment extracted from Haematococcus pluvialis, astaxanthin is one of the most powerful known natural antioxidants.
  • It protects cell membranes and mitochondria from oxidative stress induced by UV exposure, pollution, and psychological stress.
  • Its antioxidant and anti-inflammatory activity reduces free radical formation, prevents photoageing, and improves skin microcirculation.
  • Astaxanthin also enhances complexion uniformity and reduces age-related pigmentation marks.
  • The intestinal microbiota directly influences skin health through immune regulation and reduced systemic inflammation.
  • Dysbiosis promotes skin hypersensitivity, acne, rosacea, and impaired healing.
  • The probiotic strains selected in SKIN help reduce intestinal permeability, decrease inflammatory mediators, and strengthen the skin barrier via the gut–skin axis.
  • They also optimise nutrient absorption essential to dermal regeneration.

Scientific studies

1 — 3

Randomised controlled trial (2023) — Gao et al., Journal of Cosmetic Dermatology, Kyoto Prefectural University of Medicine
Oral hyaluronic acid significantly improves skin hydration and elasticity after 8 to 12 weeks of supplementation, with cumulative effects and a favourable safety profile.

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