Chronic Fatigue & Seasonal Affective Disorder

Persistent fatigue — whether physical or mental, chronic or seasonal — rarely results from a simple lack of rest. It most often reflects a global imbalance involving the neuro-endocrine axis (stress, cortisol), neurotransmitters (serotonin, melatonin, dopamine), the gut microbiota, hormonal balance and sometimes low-grade inflammation. These factors disrupt energy regulation, affect mood and reduce recovery capacity.

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