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Founder of METHODE ESPINASSE
Creator of Cellular Nutrition®
A global scientific & medical expertise
Doctor of Pharmacy
Graduate in micronutrition
Graduate in predictive and preventive medicine
Pioneer in micronutrition and first to offer consultations in Paris
Specialist in food intolerances and intestinal microbiota
Expert in biohacking, personalized health and longevity
More than 20 years of experience
More than 20,000 patients
More than 15,000 food intolerance tests
Originally from Auvergne, from a family attached to the land and respect for life, Dr. Espinasse early on perceived the close link between nutrition,
environment and health. Doctor of pharmacy, she then specialized in micronutrition and predictive and preventive medicine.
A pioneer in Paris, she was the first to offer functional micronutrition consultations, orienting her practice towards understanding
the fine interactions between nutrition, cellular biology and metabolism.
Visionary, she became interested in food intolerances and the intestinal microbiota from the early 2000s, well before research
confirmed their determining role in overall health and longevity. Her practice is inspired by the Hippocratic principle « Let food be thy first medicine », enriched by contemporary knowledge in aging biology, epigenetics and preventive medicine.
She carries a contemporary vision of integrative health, combining scientific rigor, intelligence of life and personalization.
Dr. Espinasse has supported more than 20,000 patients in optimizing their overall health. Building on this clinical experience, she evolved her approach towards a new paradigm: Cellular Nutrition®.
This approach considers the cell as the fundamental unit of health and aging. Each imbalance – hormonal, immune, digestive or emotional – originates in an alteration of cellular function: mitochondrial energy deficit, oxidative stress, dysregulation of signaling pathways or deficiency in essential micronutrients.
Cellular Nutrition aims to restore these functions by acting on:
— mitochondrial bioenergetics: ATP production, mitochondrial renewal, stimulation of biogenesis via PGC-1α and AMPK pathways;
— antioxidant protection: activation of endogenous defenses (SOD, glutathione, catalase) and neutralization of reactive oxygen species;
— modulation of low-grade inflammation, through control of pro-inflammatory cytokines and restoration of cell membranes rich in polyunsaturated fatty acids;
— the balance of the microbiota and liver, true organs of longevity, on which depend the bioavailability of nutrients, detoxification and neuro-immune regulation;
— hormonal and neuromediator homeostasis, essential for emotional stability, sleep and cognitive performance.
Longevity is not just about lifespan: it depends on the ability of cells to maintain their functions over time. Dr. Espinasse adopts an integrative approach based on the major biological levers identified by contemporary research:
— maintenance of cellular energy metabolism (mitochondrial function, NAD⁺, coenzyme Q10, precursor amino acids).
— reduction of oxidative stress and chronic inflammation, true accelerators of cellular aging.
— modulation of longevity signaling pathways (AMPK, sirtuins, mTOR, IGF-1), on which depends the balance between anabolism, repair and autophagy.
— preservation of the intestinal microbiota and epithelial barrier, determining for immunity, neurogenesis and metabolism.
— restoration of hormonal and circadian balance, pillars of tissue regeneration and deep sleep.
This integrative approach helps slow cellular senescence, optimize mitochondrial bioenergy and regulate the epigenetic mechanisms involved in aging.
Dr. Espinasse has developed a range of highly bioavailable supplements, derived from cellular biology research. Each formula is based on a synergy of active ingredients capable of supporting mitochondrial energy production (CoQ10, alpha-lipoic acid, L-carnitine), activating antioxidant pathways (vitamins C and E, polyphenols, astaxanthin), restoring cell membranes (phospholipids, omega-3), modulating inflammation (curcumin, berberine, zinc) and balancing the microbiota (selected probiotic strains).
Each formula is designed to nourish cells at the source and restore overall biological balance. Méthode Espinasse also offers personalized programs
combining dietary advice and targeted supplementation, to create a synergy of actions to optimize health, performance and longevity according to individual needs.
This is the very philosophy of applied Cellular Nutrition®: acting upstream, at the cellular level, to preserve vitality, beauty and longevity.
Méthode Espinasse thus embodies a new approach to health: preventive, scientific and personalized.
Dr. Espinasse holds a doctorate in pharmacy, complemented by two university degrees in Micronutrition and Predictive, Preventive and Personalized Medicine. She regularly participates in international congresses on longevity, cellular nutrition, microbiota and biohacking. Her work integrates the most recent research on aging biology, inflammatory markers, glycation, mitochondrial dysregulation and interactions between nutrition and gene expression.
She also leads masterclasses, in Paris and internationally, dedicated to longevity, microbiota, metabolism and nutritional neuroendocrinology. Author of several bestselling books (J'arrête le sucre, My Good Détox, Les secrets de l'équilibre féminin…), she shares a scientific and pragmatic vision of health. She regularly contributes to specialized media (Le Figaro, ELLE, Les Échos, Santé Magazine…), contributing to the spread of preventive and regenerative medicine.
