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Moon

Sleep Regulation and Quality

60 gélules pour 1 mois

MOON is the advanced Cellular Nutrition protocol formulated by Dr. Espinasse to restore the body’s natural sleep rhythm and support optimal nocturnal recovery, by acting on the neurobiological mechanisms involved in sleep onset, sleep continuity, and circadian regulation.


This food supplement combines melatonin, gentle calming plants — Hawthorn and California poppy (Eschscholtzia) — with selected probiotic strains, chosen for their complementary and synergistic actions: together, they promote circadian synchronisation, nervous system relaxation, reduction of evening mental hyperactivity, and improvement of deep, restorative sleep, without dependency.


By addressing circadian rhythm disruption, night-time stress, neuronal hyperexcitability, and imbalance of the gut–brain axis, MOON helps facilitate falling asleep, reduce nocturnal awakenings, and enhance physical, cognitive, and emotional recovery; its integrative formulation is particularly suited to sleep disturbances linked to stress, jet lag, nervous exhaustion, or hormonal transitions.


MOON is recommended in cases of difficulty falling asleep or fragmented sleep, evening stress and mental overactivity, jet lag or circadian rhythm disruption, as well as sleep disorders associated with menopause or nervous exhaustion; it forms part of a global restorative sleep approach, supporting long-term nervous system balance and nightly cellular regeneration.

Key bioavailable active ingredients HAWTHORN / MELATONIN / CALIFORNIA POPPY

single bottle 50.00€
3-bottle pack -10% on pack of 3 : 45.00€ per unit instead of 50.00€
135.00€ 150€
select a quantity
vegetable capsule
vegan
gluten-free
lactose-free
GMO-free

Integrated actions & benefits

MOON works synergistically on both the central and peripheral drivers of sleep disturbances, supporting circadian rhythm regulation, nervous system calming and the body’s natural night-time recovery processes. Its formulation is designed to restore physiological synchronisation of the sleep–wake cycle, which is essential for natural sleep onset and high-quality rest. MOON helps reduce evening mental overactivity, ease nervous tension and facilitate a smooth transition into sleep, without excessive sedative effects or dependency. By promoting more continuous and deeper sleep, it supports physical, cognitive and emotional recovery phases, which are often disrupted by stress, hormonal imbalance or prolonged overload. By integrating the gut–brain axis, MOON also contributes to more stable nocturnal neurochemical regulation, which plays a key role in sleep continuity and stress management. This global approach helps sustainably improve sleep quality, optimise cellular regeneration and restore balance across the body’s major biological rhythms. MOON is therefore a key supplement for calming the nervous system, restoring restorative sleep and supporting overnight recovery of both body and mind.

Integrated mechanisms of action

Regulation of circadian rhythm: normalisation of melatonin secretion for faster sleep onset and deeper rest.

Nervous system relaxation: modulation of GABA and reduction of neuronal hyperexcitability (hawthorn, Eschscholtzia).

Reduction of nocturnal oxidative stress: antioxidant and anti-inflammatory effects of melatonin and plant flavonoids.

Gut–brain axis support: improved neurochemical communication between gut and brain (probiotics).

Scientifically documented active ingredient synergy

  • Naturally secreted by the pineal gland at nightfall, melatonin regulates the sleep–wake cycle and acts as a biological synchroniser.
  • Its production can be disrupted by stress, artificial light, screens, or jet lag.
  • Physiological supplementation helps reduce sleep-onset latency, restore a stable sleep cycle, and improve the quality of deep sleep.
  • Melatonin also exerts antioxidant and anti-inflammatory activity, supporting neuronal protection and nocturnal cellular regeneration.
  • Traditionally used to calm states of nervous tension, hawthorn exerts a gentle sedative effect on both the nervous and cardiac systems.
  • Its flavonoids and procyanidins act on GABAergic receptors, promoting relaxation and reducing palpitations linked to anxiety.
  • It helps ease internal tension, stabilise heart rhythm, and encourage natural sleep onset without dependency.
  • Eschscholtzia contains alkaloids (protopine, californidine) that bind to GABA receptors, the main inhibitory neurotransmitter system of the central nervous system.
  • It promotes falling asleep, reduces nocturnal awakenings, and improves REM sleep quality.
  • Its mild anxiolytic action makes it a natural alternative to sleeping pills, without daytime drowsiness or dependency risk.
  • The gut microbiota plays a key role in the synthesis of neurotransmitters involved in sleep regulation, such as serotonin and GABA.
  • Microbial imbalances can impair this production and sustain low-grade inflammation, a contributing factor to chronic insomnia.
  • The probiotic strains in MOON were selected for their ability to modulate serotonin production, improve stress tolerance, and regulate vagal nerve signalling, thus contributing to more stable, restorative sleep.

Scientific studies

1 — 3

Meta-analysis (2024) — Zisapel et al., Sleep Medicine Reviews, Harvard Medical School & University of Oxford
Melatonin significantly improves sleep-onset latency and overall sleep quality, particularly in individuals with insomnia or jet lag, with an excellent safety profile.

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