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Flam

Inflammation

60 gélules pour 1 mois

FLAM is the advanced Cellular Nutrition protocol formulated by Dr. Espinasse to act deeply on the cellular mechanisms of inflammation and oxidative stress, and to support long-term balance in chronic inflammatory terrain.


This food supplement combines key anti-inflammatory botanical extracts, Turmeric and Boswellia, the adaptogenic plant Panax Ginseng, and selected probiotic strains, chosen for their complementary and synergistic actions: together, they modulate inflammatory signalling pathways, regulate pro-inflammatory cytokine production, and protect tissues from oxidative damage, while preserving digestive and immune balance.


By targeting low-grade inflammation, immune dysregulation, and disruption of the gut–immune axis, FLAM helps improve joint mobility, muscle and digestive comfort, and the body’s recovery capacity over time; its integrative formulation is particularly suited to chronic joint or muscle pain, inflammatory digestive discomfort, fatigue associated with inflammatory terrain, or slow recovery following physical exertion or prolonged stress.


FLAM is recommended in cases of persistent joint or muscle pain, digestive inflammation or intestinal discomfort, chronic fatigue linked to inflammatory imbalance, as well as difficult recovery after effort or prolonged stress; it forms part of a global inflammatory resilience approach, supporting long-term cellular, immune, and metabolic balance.

Key bioavailable active ingredients TURMERIC / BOSWELLIA / GINSENG

single bottle 50.00€
3-bottle pack -10% on pack of 3 : 45.00€ per unit instead of 50.00€
135.00€ 150€
select a quantity
vegetable capsule
vegan
gluten-free
lactose-free
GMO-free

Integrated actions & benefits

By addressing the underlying drivers of inflammation rather than masking symptoms alone, FLAM supports a gradual return to cellular and metabolic balance. Its formulation targets the key signalling pathways involved in chronic inflammation and oxidative stress, which are commonly associated with persistent pain, joint stiffness, digestive discomfort and background fatigue. FLAM helps modulate the production of pro-inflammatory mediators and limit excessive inflammatory responses, while preserving tissue integrity and mucosal health. This regulatory action supports a progressive improvement in mobility, a reduction in muscular tension and better digestive tolerance, particularly in individuals with a chronically inflamed or stress-sensitised terrain. By integrating the gut–immune–inflammation axis, FLAM also contributes to strengthening the intestinal barrier and reducing low-grade inflammation driven by increased gut permeability. Its plant-based and probiotic synergy acts as a global regulator of inflammatory processes, sustainably supporting vitality, joint comfort and the body’s capacity for recovery. FLAM is therefore a key supplement for restoring the body’s resilience in the face of chronic inflammation and supporting a return to more balanced physiological functioning.

Integrated mechanisms of action

Inhibition of pro-inflammatory mediators: reduction of NF-κB, COX-2, and 5-LOX activity (Curcuma, Boswellia).

Immune modulation: regulation of cytokine production (Ginseng, probiotics).

Antioxidant action: limitation of oxidative stress responsible for tissue damage.

Joint and muscle protection: improved flexibility and reduced stiffness.

Scientifically documented active ingredient synergy

  • Curcumin, the main active polyphenol in turmeric, exerts a well-documented anti-inflammatory effect. It inhibits COX-2 and 5-LOX enzymes, reduces the release of pro-inflammatory cytokines (IL-1β, IL-6, TNF-α), and protects cell membranes from lipid peroxidation.
  • Its effects are particularly notable on joint and muscle pain, digestive inflammation (colopathy, intestinal hypersensitivity), and systemic oxidative stress.
  • Combined with probiotics and other phytotherapeutic agents, it enhances digestive tolerance and curcuminoid bioavailability.
  • Boswellia resin, rich in boswellic acids, acts on a pathway complementary to turmeric by inhibiting 5-lipoxygenase (5-LOX), responsible for leukotriene synthesis.
  • This gives Boswellia specific efficacy on joint pain, tendinitis, and muscle inflammation. Numerous studies have confirmed its ability to improve mobility, reduce swelling, and decrease stiffness, while preserving the gastric mucosa — a major advantage over conventional anti-inflammatories.
  • Ginseng provides a dual regulatory action: it modulates immune response and supports cellular energy production. Its ginsenosides regulate cytokine production and limit excessive inflammatory reactions.
  • At the same time, its adaptogenic role helps the body better manage physical and psychological stress — both key contributors to chronic inflammation. It also promotes muscle recovery and helps maintain overall vitality.
  • An imbalanced microbiota can increase intestinal permeability and activate the immune system, fostering chronic inflammation.
  • The probiotic strains in FLAM were selected for their ability to regulate mucosal immune response, reduce the production of pro-inflammatory lipopolysaccharides (LPS), and strengthen the intestinal barrier.
  • This “gut–brain–immunity” approach is an essential lever to sustainably modulate systemic inflammatory processes.

Scientific studies

1 — 3

Meta-analysis (2023) — Haroyan et al., Frontiers in Immunology
Curcumin significantly reduces pain and joint stiffness in knee osteoarthritis, with efficacy comparable to NSAIDs and a superior safety profile.

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