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Age

Antioxidant Defence and Ageing Support

60 gélules pour 1 mois

AGE is the advanced Cellular Nutrition protocol formulated by the Dr. Espinasse to protect cells from the core biological mechanisms of ageing and support long-term cellular longevity.


This food supplement combines powerful cellular antioxidants and protectors, Resveratrol, Astragalus, and Quercetin, with selected probiotic strains, chosen for their complementary and synergistic actions: together, they form a true anti-ageing shield that acts at the cellular level to preserve tissue integrity, metabolic resilience, and biological youthfulness.


By targeting oxidative stress, low-grade inflammation, and metabolic ageing, AGE supports the biological mechanisms of cellular longevity and the body’s adaptive capacity in response to internal and environmental stressors: its integrative formulation is particularly suited to periods of chronic fatigue, sustained stress, or accelerated ageing processes.


AGE is recommended in cases of chronic fatigue and reduced vitality, premature skin ageing, ongoing oxidative stress, as well as for the prevention of cellular and inflammatory ageing processes: it forms part of a global longevity approach, supporting cellular health at the core of long-term biological performance.

Key bioavailable active ingredients RESVERATROL / ASTRAGALUS / QUERCETIN

single bottle 75.00€
3-bottle pack -10% on pack of 3 : 67.50€ per unit instead of 75.00€
202.50€ 225€
select a quantity
vegetable capsule
vegan
gluten-free
lactose-free
GMO-free

Integrated actions & benefits

Through its unique formulation, AGE works at the heart of the fundamental mechanisms of cellular ageing, targeting the biological processes involved in the progressive deterioration of tissues. It supports cellular longevity pathways, helps protect DNA integrity and contributes to maintaining efficient mitochondrial function — which is essential for energy production and cellular resilience. AGE strengthens the body’s endogenous antioxidant systems, helping limit the accumulation of oxidative damage associated with premature ageing, chronic fatigue and low-grade inflammation. By modulating inflammatory responses and improving the quality of energy metabolism, it promotes a more stable cellular environment, conducive to regeneration and the preservation of vitality. By integrating the gut–cell axis, AGE also contributes to reducing age-related systemic inflammation and optimising the bioavailability of protective nutrients. It is a key supplement for preserving cellular health, supporting functional longevity and slowing the effects of ageing in a measurable, progressive and sustainable way.

Integrated mechanisms of action

Activation of cellular longevity pathways: stimulation of sirtuins and telomerase (resveratrol, astragalus).

Mitochondrial protection: improved cellular respiration and reduced oxidative stress.

Global antioxidant effect: neutralisation of free radicals and support for enzymatic defences (SOD, catalase, glutathione peroxidase).

Anti-inflammatory and senolytic action: reduction of pro-inflammatory cytokines and elimination of senescent cells (quercetin).

Scientifically documented active ingredient synergy

  • A natural polyphenol extracted from grape skin, resveratrol is known for its role in activating longevity enzymes such as SIRT1.
  • It stimulates DNA repair mechanisms, enhances mitochondrial function, and reduces free radical production.
  • Resveratrol also supports insulin sensitivity and energy metabolism regulation, thereby extending cellular lifespan.
  • Its caloric restriction–mimetic effect makes it a key ally for longevity and for slowing both skin and metabolic ageing.
  • A flagship plant of traditional Chinese medicine, Astragalus has remarkable immunostimulant, adaptogenic, and anti-ageing properties.
  • Its astragalosides and polysaccharides stimulate telomerase production, an enzyme that protects and maintains telomere length — biological markers of cellular longevity.
  • It also enhances mitochondrial function, supports immunity, and limits the effects of chronic oxidative stress.
  • Astragalus thus acts as a global cellular protector, improving vitality, recovery, and resistance to environmental stress.
  • Quercetin is an antioxidant flavonoid found in plants such as onions, apples, and capers.
  • It inhibits pro-oxidant enzymes (COX, LOX) and reduces the release of inflammatory cytokines (IL-6, TNF-α).
  • Its senolytic effects — eliminating dysfunctional senescent cells — help restore cellular communication and tissue quality.
  • Quercetin also works synergistically with resveratrol and astragalus to strengthen mitochondrial protection and DNA stability.
  • The gut microbiota directly influences systemic ageing by modulating oxidative stress, inflammation, and energy metabolism.
  • With age, bacterial diversity declines, promoting intestinal permeability and the diffusion of pro-inflammatory toxins (LPS).
  • The probiotics included in AGE help reduce chronic inflammation, strengthen the intestinal barrier, and support antioxidant bioavailability.
  • This integrated “gut–cell–mitochondria” approach is a key strategy for maintaining cellular youthfulness.

Scientific studies

1 — 3

Systematic review (2023) — Li et al., Nutrients, Harvard Medical School & University of Bologna
Resveratrol activates SIRT1 and AMPK pathways, improves mitochondrial function and reduces age-related inflammatory markers.

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