Livraison offerte en France métropolitaine à partir de 80€ d'achat Anglais

Oil

Female Cycle, Menopause and Skin Health

60 gélules pour 1 mois

OIL is the advanced Cellular Nutrition protocol formulated by Dr. Espinasse, based on highly bioavailable evening primrose oil, a natural source of gamma-linolenic acid (GLA), to support hormonal, inflammatory, and skin regulation, particularly in women.


This food supplement provides essential fatty acids required for the synthesis of type-1 prostaglandins (PGE1), which play a key role in hormonal balance, inflammatory modulation, and cellular membrane integrity: its action helps stabilise hormonal fluctuations, reinforce the skin’s lipid barrier, and limit low-grade chronic inflammation.


By addressing functional hormonal imbalance, skin dryness and sensitivity, inflammatory susceptibility, and emotionally driven hormonal fluctuations, OIL supports menstrual comfort, menopausal transition, and long-term skin quality; its formulation is particularly suited to premenstrual syndrome, perimenopause, and menopause-related changes.


OIL is recommended in cases of premenstrual syndrome, perimenopausal or menopausal symptoms, dry, sensitive, or inflammation-prone skin, as well as hormonal imbalance associated with fatigue or emotional instability; it forms part of a global feminine balance approach, supporting hormonal harmony, skin comfort, and emotional stability throughout every stage of a woman’s life.

Key bioavailable active ingredients EVENING PRIMROSE OIL

single bottle 40.00€
3-bottle pack -10% on pack of 3 : 36.00€ per unit instead of 40.00€
108.00€ 120€
select a quantity
vegetable capsule
vegan
gluten-free
lactose-free
GMO-free

Integrated actions & benefits

Through its targeted supply of essential fatty acids and its central role in prostaglandin regulation, OIL acts at the source of female hormonal and inflammatory imbalances. Its formulation supports the physiological mechanisms involved in cycle regulation, inflammation modulation and the maintenance of cellular membrane integrity — all of which are essential for hormonal balance and skin health. OIL helps improve menstrual comfort and tolerance to hormonal fluctuations, while also supporting skin quality and emotional stability. By reinforcing the skin’s lipid barrier and limiting transepidermal water loss, it contributes to skin that is more supple, better hydrated and less reactive, particularly during periods of oestrogen decline or inflammatory stress. By supporting the key stages of hormonal life — from premenstrual syndrome through perimenopause and menopause — OIL provides natural support for female biological balance. It is a key supplement for sustainably preserving hormonal comfort, skin quality and emotional equilibrium, while respecting the physiological mechanisms specific to each phase of a woman’s life.

Integrated mechanisms of action

Female hormonal regulation: modulation of prostaglandin production and support of the luteal phase.

Gentle anti-inflammatory action: reduction of pro-inflammatory cytokines and restoration of cell membrane integrity.

Improved skin comfort: reinforcement of the lipid barrier and reduction of skin dryness or sensitivity.

Cycle and menopause support: alleviation of premenstrual symptoms and hormonal imbalances related to oestrogen deficiency.

Scientifically documented active ingredient synergy

  • Evening primrose oil is extracted from the seeds of Oenothera biennis, a plant naturally rich in polyunsaturated fatty acids, notably linoleic acid (LA, 70–75%) and gamma-linolenic acid (GLA, 8–10%).
  • GLA is a precursor of type-1 prostaglandins (PGE1), which exert anti-inflammatory and regulatory effects on hormonal, circulatory and skin functions.
  • In women, it helps to:
    • Reduce premenstrual syndrome symptoms, including breast tenderness, irritability and pelvic discomfort.
    • Alleviate menopausal symptoms, such as hot flushes and skin dryness.
    • Improve skin elasticity, softness and hydration, often compromised by hormonal deficiency or lipid imbalance.
  • GLA also promotes the synthesis of anti-inflammatory prostaglandins and modulates immune responses, helping to prevent low-grade chronic inflammatory states affecting the skin, joints and mucous membranes.
  • Evening primrose oil acts directly on the structure of the skin barrier by strengthening ceramides and phospholipids within the stratum corneum. It enhances cellular cohesion and limits transepidermal water loss (TEWL), resulting in skin that is more supple, less reactive and better hydrated.
  • Several clinical studies have demonstrated its effectiveness in conditions such as atopic eczema, dryness, redness and skin irritation.

 

  • By modulating prostaglandin production, evening primrose oil contributes to improved menstrual cycle regulation and a reduction in mood fluctuations associated with hormonal variations.
  • It also supports liver function involved in oestrogen metabolism, thereby promoting overall hormonal balance and helping to reduce symptoms linked to relative oestrogen dominance, such as breast tenderness, irregular cycles and irritability.

Scientific studies

1 — 3

Meta-analysis (2024) — Almeida et al., Phytotherapy Research, University of Nottingham & Seoul National University
Supplements rich in gamma-linolenic acid (GLA) derived from evening primrose and borage improve skin dryness as well as premenstrual syndrome symptoms, with good overall tolerability.

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